
Topical Cream · 4%

Sildenafil relaxes blood vessels and increases local blood flow. Applied as a cream rather than swallowed, the effect concentrates where it is needed and systemic exposure stays low. It is used on demand, shortly before activity, rather than daily.


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Apply a small amount to the external genital area 15 to 30 minutes before activity; use no more than once daily
Sildenafil is FDA approved as an oral tablet for erectile dysfunction in men. There is no FDA approved topical sildenafil cream. That means no FDA reviewed safety label exists for this preparation, and no side effect rate has been established for applying it to the skin.
Tell your care team straight away if you get chest pain, dizziness or fainting, a severe headache that will not settle, or swelling or a rash where you applied it.
Do not take this if you or your partner take nitrates in any form, or you have reacted badly to sildenafil before.
This is not a complete list of side effects. Message your care team about any symptom that worries you. What we dispense is a compounded preparation made by a licensed US pharmacy. Compounded medications are not approved by the FDA for safety, efficacy or quality.
The cream acts locally where it is applied, so systemic exposure is much lower. That means fewer of the whole-body effects associated with oral tablets, but also a more localised result.
Most people apply it 15 to 30 minutes beforehand. Warmth or tingling at the site is expected and usually means it is working.
Transfer is possible. Allow it to absorb fully before contact, and discuss this with your clinician if it is a concern.
Nitrates are a hard contraindication with sildenafil in any form. Tell your clinician about everything you take, including anything for chest pain or blood pressure.

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