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Relieve Menopause Symptoms

DHEA Vaginal Suppository

Vaginal Suppository · 6.5 mg

  • Eases dryness and discomfort
  • Converted locally in the tissue
  • Simple nightly routine
★★★★★
4.9 · 1,200+ member reviews

Choose your plan

1-month
Billed monthly
$
180
/mo
180
3-month
Billed quarterly
$
126
/mo
180
6-month
Billed twice a year
$
104
/mo
180
12-month
Billed annually
$
87
/mo
180
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DHEA Vaginal Suppository
womens-dhea-vaginal-suppository
Cancel anytime · Free shipping · Prescribed only if appropriate
US-licensed clinicians
Ships from US pharmacies
HSA/FSA eligible

What is Vaginal DHEA?

DHEA is a precursor hormone. Placed vaginally, it is converted inside the tissue itself into small amounts of oestrogen and testosterone, which restores comfort and elasticity locally. Because the conversion happens in the tissue rather than the bloodstream, it appeals to women who want to avoid a systemically labelled oestrogen product.

What to expect

What to expect

  • Nightly at bedtime — Lying down afterwards makes it more comfortable.
  • Converted in the tissue — The effect stays local rather than systemic.
  • Four to twelve weeks — Improvement is gradual, not immediate.
  • Discharge is expected — The most common effect and usually manageable.

How it works

Online consultation with a licensed clinician
Step 1

Online consultation

Answer a few health questions — a licensed provider reviews online. No waiting rooms.

A few minutes
Prescription approved
Step 2

Prescription approved

Once approved, your medication ships discreetly to your door.

Within 72 hours
Feeling the differenceFeeling the difference
Step 3

Feel the difference

Physician-guided support and check-ins keep results on track.

2–5 business days

Dosing, safety & what's inside

How to dose

Insert 1 suppository vaginally at bedtime, nightly, using the applicator provided

Risks & side effects

Tell your care team straight away if you get any vaginal bleeding after menopause, you find a new breast lump, your clinician reports an abnormal Pap result, or you get vaginal discharge with pain, fever or an odor.

Common side effects

  • vaginal discharge
  • an abnormal Pap smear result

Rare but serious

  • abnormal cervical cells on a Pap smear
  • estrogen is produced when your body breaks this down, and it has not been studied in women with a history of breast cancer

Do not take this if you have vaginal bleeding that has not been looked into.

This is not a complete list of side effects. Message your care team about any symptom that worries you.

Common questions

Is this a hormone?

DHEA is a precursor that the body converts into oestrogen and testosterone. Placed vaginally, that conversion happens within the tissue, so the effect is local.

When do I use it?

Once nightly at bedtime, using the applicator provided. Lying down afterwards reduces leakage.

How long before it works?

Most people notice improvement over four to twelve weeks of consistent nightly use. It is not a fast-acting treatment.

What is the most common side effect?

Vaginal discharge, which is expected and usually manageable. Persistent irritation is worth reporting.

Start your plan today

1-month
$
/mo
Billed monthly
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1mo
DHEA Vaginal Suppository
womens-dhea-vaginal-suppository
Most popular
3-month
$
/mo
Billed quarterly
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3mo
DHEA Vaginal Suppository
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Best value
6-month
$
87
/mo
Billed twice a year
Add to cart
6mo
87
DHEA Vaginal Suppository
womens-dhea-vaginal-suppository

Built by a health team that's actually on your side

Prof Brian Kennedy, PhD

Prof Brian Kennedy, PhD

Scientific Advisor

Globally recognized aging biologist and former CEO of the Buck Institute for Research on Aging, renowned for pioneering research on sirtuins, mTOR, and healthy aging.

Matt Kaeberlein

Matt Kaeberlein

Scientific Advisor

World-leading biogerontologist and Founding Director of the Healthy Aging & Longevity Research Institute, celebrated for uncovering the biological mechanisms of aging.

Rhonda Collins, FNP-C

Rhonda Collins, FNP-C

Care Team Lead

Board-certified Family Nurse Practitioner with 15+ years of clinical experience, specializing in preventative wellness and biomarker-driven personalized care.