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Lose Weight

Tirzepatide + B12

Injection · 10 mg/mL (tirzepatide)

  • Dual-action tirzepatide compound
  • B12 to support daily energy
  • Convenient weekly injection
★★★★★
4.9 · 1,200+ member reviews

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1-month
Billed monthly
$
379
/mo
379
3-month
Billed quarterly
$
349
/mo
379
Billed twice a year
$
319
/mo
379
Billed annually
$
299
/mo
379
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Tirzepatide + B12
care-tirzepatide
Cancel anytime · Free shipping · Prescribed only if appropriate
US-licensed clinicians
Ships from US pharmacies
HSA/FSA eligible

What is Tirzepatide?

A dual GIP/GLP-1 agonist — the most effective weight-loss injection studied to date. Reduces appetite, improves insulin sensitivity, and supports meaningful, sustained loss. Our formulation adds B12 and glycine to reduce side effects and preserve muscle.

What to expect

What to expect

  • A starting dose that steps up — Treatment begins low and increases gradually so your body adjusts and side effects stay manageable.
  • Appetite changes first — Most people notice reduced appetite and earlier fullness before they notice the scale moving.
  • Steady, not sudden — A healthy pace is roughly one to two pounds a week. Faster is not better.
  • Nausea is common early — It usually settles within a few weeks and eases with smaller, slower meals.

How it works

Online consultation with a licensed clinician
Step 1

Online consultation

Answer a few health questions — a licensed provider reviews online. No waiting rooms.

A few minutes
Prescription approved
Step 2

Prescription approved

Once approved, your medication ships discreetly to your door.

Within 72 hours
Feeling the differenceFeeling the difference
Step 3

Feel the difference

Physician-guided support and check-ins keep results on track.

2–5 business days

Dosing, safety & what's inside

How to dose

Inject 50 units (5 mg) subcutaneously once a week for 12 weeks; titrate at clinician discretion; lowest effective dose; do not escalate with active side effects

Risks & side effects

Tirzepatide caused thyroid C-cell tumors in rats. Whether that happens in people is not known.

Tell your care team straight away if you feel a lump or swelling in your neck, your voice goes hoarse or swallowing becomes hard, you get severe stomach pain that will not stop, you cannot keep up with vomiting or diarrhea, you get pain in your upper right belly or your eyes turn yellow, or you get a rash with swelling of the face or lips or trouble breathing.

Common side effects

  • nausea
  • diarrhea
  • vomiting
  • constipation
  • abdominal pain
  • indigestion
  • injection site reactions
  • fatigue
  • hair loss

Rare but serious

  • acute pancreatitis
  • gallbladder disease
  • kidney injury from fluid loss
  • low blood sugar
  • worsening diabetic eye disease
  • food left in the stomach during anesthesia

Do not take this if you or a family member has had medullary thyroid carcinoma, you have Multiple Endocrine Neoplasia syndrome type 2, or you have reacted badly to tirzepatide before.

This is not a complete list of side effects. Message your care team about any symptom that worries you. What we dispense is a compounded preparation made by a licensed US pharmacy. Compounded medications are not approved by the FDA for safety, efficacy or quality.

Common questions

How is tirzepatide different from semaglutide?

Tirzepatide acts on two gut hormone receptors, GIP and GLP-1, rather than one. In trials it produced greater average weight loss, though individual response varies and side effects are broadly similar.

How often do I inject?

Once weekly, as a small subcutaneous injection at home. This formulation also includes glycine and B12.

How quickly will I lose weight?

Steadily, over months. The early weeks are about stepping the dose up and letting your body adjust rather than chasing the scale.

What are the common side effects?

Nausea, constipation, diarrhoea and reflux are the most common, and are usually worst in the days after a dose increase. Eating smaller portions more slowly helps. Tell your clinician about anything severe or persistent.

What happens if I stop?

Appetite generally returns and weight regain is common without other changes in place. This is why the habits you build during treatment matter as much as the medication.

Who should not take this?

It is not appropriate if you have a personal or family history of medullary thyroid carcinoma or MEN 2, and it is not for use in pregnancy. Your intake covers the full list of contraindications.

Start your plan today

1-month
$
/mo
Billed monthly
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1mo
Tirzepatide + B12
care-tirzepatide
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3-month
$
/mo
Billed quarterly
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3mo
Tirzepatide + B12
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Best value
6-month
$
299
/mo
Billed twice a year
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6mo
299
Tirzepatide + B12
care-tirzepatide

Built by a health team that's actually on your side

Prof Brian Kennedy, PhD

Prof Brian Kennedy, PhD

Scientific Advisor

Globally recognized aging biologist and former CEO of the Buck Institute for Research on Aging, renowned for pioneering research on sirtuins, mTOR, and healthy aging.

Matt Kaeberlein

Matt Kaeberlein

Scientific Advisor

World-leading biogerontologist and Founding Director of the Healthy Aging & Longevity Research Institute, celebrated for uncovering the biological mechanisms of aging.

Rhonda Collins, FNP-C

Rhonda Collins, FNP-C

Care Team Lead

Board-certified Family Nurse Practitioner with 15+ years of clinical experience, specializing in preventative wellness and biomarker-driven personalized care.