Levothyroxine
Tablet · 50 mcg (25-100 mcg range)
- Standard thyroid replacement
- Restores energy and metabolism
- Once-daily tablet
Choose your plan
This treatment starts with labs
Your clinician needs recent blood work to prescribe safely. Two ways to get it done:
What is Levothyroxine (T4)?
The first-line replacement for hypothyroidism confirmed on your Vitals Vault thyroid panel. Taken each morning on an empty stomach; dose is fine-tuned on TSH/Free T4 labs at 6–8 weeks.
What to expect
- Empty stomach, same time — Consistency in how you take it matters as much as the dose.
- Six weeks to steady state — Labs are usually rechecked around six weeks after a change.
- Dose adjustments are normal — Finding the right dose is a process, not a single decision.
- Mind the interactions — Calcium, iron and antacids need at least four hours' separation.
From order to optimized
Health assessment panel
Quick lab panel at 2,000+ locations near you — or upload recent bloodwork and we may use your existing results.
Review your results
A licensed clinician reviews your levels, symptoms and goals, builds your personalized plan, and ships it to your door.
Feel the difference
Most members notice improvements within weeks. We recheck labs at 90 days and fine-tune your dose.
How it works
Online consultation
Answer a few health questions — a licensed provider reviews online. No waiting rooms.
Prescription approved
Once approved, your medication ships discreetly to your door.
Feel the difference
Physician-guided support and check-ins keep results on track.
Dosing, safety & what's inside
Take 1 tablet by mouth every morning on empty stomach, 30-60 minutes before food; dose adjusted on TSH/Free T4 at 6-8 weeks
Thyroid hormone must not be used for weight loss. Doses larger than your body needs can be dangerous, especially alongside other weight loss medication.
Tell your care team straight away if you get chest pain, a pounding or racing or irregular heartbeat, shortness of breath, tremor or sweating or feeling overheated, or you lose weight without meaning to and cannot sleep.
Common side effects
- palpitations
- a fast heart rate
- tremor
- muscle weakness
- headache
- nervousness
- insomnia
- diarrhea
- feeling too warm
Rare but serious
- heart rhythm problems, particularly if you are older or have heart disease
- worsening angina or heart attack
- adrenal crisis if adrenal insufficiency has not been corrected first
- loss of bone mineral density with long term over-replacement
- loss of blood sugar control if you have diabetes
Do not take this if you have adrenal insufficiency that has not been treated first.
This is not a complete list of side effects. Message your care team about any symptom that worries you.
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Common questions
How should I take it?
On an empty stomach, ideally 30 to 60 minutes before breakfast, with water. Consistency matters more than the exact time — take it the same way every day.
What interferes with absorption?
Calcium, iron, magnesium, some antacids and high-fibre foods. Separate these by at least four hours. Coffee too close to your dose can also reduce absorption.
How long before I feel different?
Some people notice change within two weeks, but the full effect of a dose takes around six weeks. That is also when your clinician will usually recheck your labs.
Will my dose stay the same?
Not necessarily. Dose adjustments guided by TSH and free T4 are normal, particularly in the first few months and after any significant weight change.
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